Inducible Lymphoid Organs (PDF) sheds new light on “inducible” lymphoid organs (ILOs): antigen presentation sites that are generated de novo in peripheral tissues under several pathogenic conditions. Accomplished immunologists show that the physiological role of these ILOs is entirely different from that of central lymphoid organs, i.e., the lymph nodes or spleen. Furthermore to the central organs, the ILOs are considered essential structures for the efficient elicitation of adaptive immune responses in lesions. The relevant chapters highlight examples from multiple sites, e.g. the skin, lung, genital tract, intestinal tract, the synovial membrane of the joints, and artificial lymph nodes. Therefore, readers of Current Topics in Microbiology and Immunology Book 426 will learn that ILO structure and function can differ substantially, depending on the context. Presenting the outcomes of the latest immunological research, the ebook offers an insightful and fascinating read for both clinicians and scientists in the areas of infectious and immune-associated diseases.
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