New experimental techniques in immunology have generated large and complex data sets that need quantitative modeling for analysis. Systems Immunology (PDF) offers a complete overview of computational immunology, from fundamental concepts to mathematical modeling at the single-molecule, organism, cellular, and population levels. Foundations of Biochemistry and Biophysics presents modern mechanistic models and their use in making predictions, designing experiments, and clarifying underlying biochemical processes. It starts with an introduction to data analysis, approximations, and assumptions used in model building. Key chapters address models and methods for studying immune responses, with basic concepts clearly defined.
Readers from quantitative biology, immunology, and applied physics will benefit from the following:
- A summary of basic concepts in modeling and data analysis.
- Coverage of topics where mechanistic modeling has added substantially to current understanding.
- Discussion of genetic diversity of the immune system, immune response at the cell population scale, cell signaling in the immune system, and ecology of host-pathogen interactions.
- Basic principles of computational immunology and modern quantitative methods for studying immune response at the single-molecule, organism, cellular, and population levels.
“Taken together, the body of information included in this ebook offers readers with a bird’s-eye view of diverse aspects of exciting work at the convergence of disciplines that will eventually lead to a future where we understand how immunity is regulated, and how we can connect this knowledge toward practical ends that reduce human suffering. I recommend the editors for putting this volume together.” — Arup K. Chakraborty, Robert T. Haslam Professor of Chemical Engineering, and Professor of Physics, Chemistry, and Biological Engineering, Massachusetts Institute of Technology, Cambridge, USA
NOTE: This sale only includes Systems Immunology: An Introduction to Modeling Methods for Scientists in PDF. No access codes included.